Similarly, maternal exposure to inflammatory insults during pregnancy leads to elevated IL-6 levels in the systemic circulation, which induces IL-6R expression in fetal intestinal epithelial stem cells, this inflammatory imprint persists into adulthood, conferring increased resistance to intestinal infections in the offspring ( in vivo models
See above for the preparation of both discontinuous and continuous gradients
These individuals can receive an injectable form of the vitamin, which altogether bypasses the gastrointestinal tract
Kirkwood PM, Gibson DA, Shaw I, Dobie R, Kelepouri O, Henderson NC, Saunders PTK (2022) Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation, Elife